Fifth Eye: Predicting Hemodynamic Instability

The Bleeding Edge of Digital Health

30-05-2023 • 41 min

In this week’s episode, host Mike Moore talks with Andrew Malcolmson and Ashwin Belle, CEO and co-founder, and Chief Analytics Officer of Fifth Eye respectively. Fifth Eye has developed an AI-powered software as a medical device platform called AHI that measures heart rate variability to detect and predict hemodynamic instability.Today, Mike, Andrew, and Ashwin discuss the science behind the AHI platform, its potential applications, and the regulatory process involved in bringing it to market. They also discuss the benefits of AHI in providing early insight into a patient's condition, allowing for more proactive interventions and potentially avoiding costly adverse events. The conversation also covers the economic benefits of AHI, including cost avoidance, better resource allocation, and avoiding unreimbursed hospital-acquired events.Notable Quotes“Having a cloud-based solution where we can get the information processing to give you results in real-time, but we also have the ability to push it back down so you can see it and, you know, react to it on whatever screen you're already looking at, whether it's your, you know, central research station or in the ICU just in the EMR, if that's the place you want it or if you want it at the patient's bedside, that's achievable as well.” – Andrew (27:56)“I think from the team's strengths perspective, we really pride ourselves on the combination of signal processing and machine learning, where most technologies tend to do a lot and they explain a lot about the machine learning because they're using flight data that comes in from each of the structured systems they do using dynamic data by using data that comes in continuously at a high speed.” – Ashwin (34:38)In This Episode(02:08) Comparison of the AHI platform to pulse oximetry(05:39) Potential applications of the AHI platform (07:59) The science and breakthrough behind the AHI platform(09:29) The experimental dataset captured by the Department of Defense to simulate hypovolemia(14:36) How Fifth Eye's platform enhances patient monitoring, aiding clinical decision-making protocols.(16:26) Real-time detection and prediction(20:05) Economic value of AHI to hospitals (22:35) Differences from other early detection systems(24:30) How Fifth Eye's AI-powered software complements existing early detection  systems(25:15) Fifth Eye's solution for processing live streaming data challenges.(29:39) Feedback from early adopters(34:02) Fifth Eye product roadmap(36:36) Biggest opportunities and challenges for AHI moving forward(39:48) Fifth Eye’s corporate culture and its importance in the current work environmentOur GuestsAshwin Belle is a highly experienced professional with over a decade of leadership in healthcare research and development. His expertise spans ideation, R&D, design, productization, clinical trials, licensing, FDA regulation, go-to-market strategy, and commercialization, all aimed at improving patient care and saving lives.With over 20 years in MedTech, Andrew Malcolmson boasts extensive expertise in both Medical Equipment and Medical Software. His background spans R&D, Sales & Marketing, and Strategic Business Development in Medical Device companies both large and small, and he has been leading the application of data science to solve today’s clinical challenges since starting one of the first Remote Monitoring & Clinical Decision Support software platforms at Covidien (Now Medtronic) in 2011.

Resources & Links
LinkedIn: Mike Moore
LinkedIn: The Bleeding Edge of Digital Health

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