I speak with guest Natalia Morone, M.D., Physician and Associate Professor of Medicine at Boston University School of Medicine and Boston Medical Center. Her research career focuses on drug free interventions to treat chronic low back pain. Her clinical trials show that meditation can reduce pain in older adults with chronic pain. Results from this work informed the American College of Physicians Guidelines to add meditation to the menu of treatments for chronic pain. Her research portfolio also extends into mindfulness delivered via electronic Health (eHealth) and telehealth. She is the Principal Investigator of the NCCIH-funded Optimizing Pain Treatment In Medical settings Using Mindfulness (OPTIMUM) pragmatic clinical trial, which we discuss.