E78: Fertility, Healthy Humans, and Ending Genetic Disease w/ Noor Siddiqui, CEO of Orchid

Erik Torenberg is joined by Noor Siddiqui, founder and CEO of Orchid, to explore groundbreaking advancements in reproductive technology, especially the world's first whole genome embryo screening. They dive into genome sequencing, IVF, and the ethical implications of these technologies, highlighting their potential to significantly reduce the incidence of major diseases. Noor shares her journey of bringing Orchid's innovative solutions from research to market, along with the importance of polygenic scores and the evolving societal views on reproductive tech.  — 🔥 Apply to join over 400 founders and Execs in the Turpentine Network: https://www.turpentinenetwork.co/ — SPONSORS: 💡 Level up your portfolio with access to pre-IPO companies via the Fundrise Innovation Fund. Access a $125M+ fund of cutting edge tech companies including AI frontrunners, now available to individual investors. Start your journey at Fundrise.com/upstream. Get first-party targeting with Brave's private ad platform: cookieless and future proof ad formats for all your business needs. Performance meets privacy. Head to https://brave.com/brave-ads/ and mention “MoZ” when signing up for a 25% discount on your first campaign. 💥 Head to Squad to access global engineering without the headache and at a fraction of the cost: head to https://choosesquad.com/ and mention “Turpentine” to skip the waitlist. — RECOMMENDED PODCASTS: 🎙️This Won't Last Eavesdrop on Keith Rabois, Kevin Ryan, Logan Bartlett, and Zach Weinberg's monthly backchannel. They unpack their hottest takes on the future of tech, business, venture, investing, and politics. Apple Podcasts: https://podcasts.apple.com/us/podcast/this-wont-last-with-keith-rabois-kevin-ryan-logan/id1765665937  Spotify: https://open.spotify.com/show/2HwSNeVLL1MXy0RjFPyOSz YouTube: https://www.youtube.com/@ThisWontLastpodcast 🎙️History 102 with WhatifAltHist Every week, creator of WhatifAltHist Rudyard Lynch and Erik Torenberg cover a major topic in history in depth -- in under an hour. This season will cover classical Greece, early America, the Vikings, medieval Islam, ancient China, the fall of the Roman Empire, and more. Subscribe on Spotify: https://open.spotify.com/show/36Kqo3BMMUBGTDo1IEYihm Apple: https://podcasts.apple.com/us/podcast/history-102-with-whatifalthists-rudyard-lynch-and/id1730633913 YouTube: https://www.youtube.com/@History102-qg5oj — LINKS: Orchid: https://www.orchidhealth.com/ — FOLLOW:  X / TWITTER: @noor_siddiqui_ (Noor) @OrchidInc (Orchid) @eriktorenberg (Erik) @upstream__pod @turpentinemedia — TIMESTAMPS (00:00) Intro (01:20) What is Orchid? (04:07) Genome sequencing for embryos: What Orchid has accomplished (06:53) The breakthrough that enabled Orchid's genome sequencing (08:25) The impact and significance of the polygenic risk score (11:48) What is IVF (15:11) Sponsors: Fundrise | Brave (17:22) Concerns and stigmas around reproductive technology (24:19 On the Gattaca future where parents create perfect children (26:02) Moral panic around longevity (28:41) Anything that can improve things can be used in very hostile ways (31:37) What are the norms around having kids going to be 30-40 years from now (35:02) Sponsor: Squad (36:12) Noor's thoughts on declining fertility rates (41:33) Matchmaking and dating (47:38) Is the decline of men a real thing? (49:31) Increasing fertility rates, moving the culture, and the negative effects of fertility collapse (1:06:56) Trying out Orchid and how the test works (1:08:11) Wrap